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Index > Protein center > TGFBR3(Gene name) > Human
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  • TGFBR3 (Gene name),
  • Transforming growth factor beta receptor type 3 (Protein name ),  TGBR3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TGFBR3;
    Protein name:
    Transforming growth factor beta receptor type 3(TGF-beta receptor type 3;TGFR-3);
    Alternative:
    Transforming growth factor beta receptor III(TGF-beta receptor type III);Betaglycan;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with TCTEX1D4.
    Function:
    Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
    Subcellular Location:
    Secreted Secreted extracellular space Cell membrane Single-pass type I membrane protein Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
    Protein Attributes:
    Sequence length:
    851
    Sequence:
    50:
    MTSHYVIAIF | ALMSSCLATA | GPEPGALCEL | SPVSASHPVQ | ALMESFTVLS | 
    100:
    GCASRGTTGL | PQEVHVLNLR | TAGQGPGQLQ | REVTLHLNPI | SSVHIHHKSV | 
    150:
    VFLLNSPHPL | VWHLKTERLA | TGVSRLFLVS | EGSVVQFSSA | NFSLTAETEE | 
    200:
    RNFPHGNEHL | LNWARKEYGA | VTSFTELKIA | RNIYIKVGED | QVFPPKCNIG | 
    250:
    KNFLSLNYLA | EYLQPKAAEG | CVMSSQPQNE | EVHIIELITP | NSNPYSAFQV | 
    300:
    DITIDIRPSQ | EDLEVVKNLI | LILKCKKSVN | WVIKSFDVKG | SLKIIAPNSI | 
    350:
    GFGKESERSM | TMTKSIRDDI | PSTQGNLVKW | ALDNGYSPIT | SYTMAPVANR | 
    400:
    FHLRLENNAE | EMGDEEVHTI | PPELRILLDP | GALPALQNPP | IRGGEGQNGG | 
    450:
    LPFPFPDISR | RVWNEEGEDG | LPRPKDPVIP | SIQLFPGLRE | PEEVQGSVDI | 
    500:
    ALSVKCDNEK | MIVAVEKDSF | QASGYSGMDV | TLLDPTCKAK | MNGTHFVLES | 
    550:
    PLNGCGTRPR | WSALDGVVYY | NSIVIQVPAL | GDSSGWPDGY | EDLESGDNGF | 
    600:
    PGDMDEGDAS | LFTRPEIVVF | NCSLQQVRNP | SSFQEQPHGN | ITFNMELYNT | 
    650:
    DLFLVPSQGV | FSVPENGHVY | VEVSVTKAEQ | ELGFAIQTCF | ISPYSNPDRM | 
    700:
    SHYTIIENIC | PKDESVKFYS | PKRVHFPIPQ | ADMDKKRFSF | VFKPVFNTSL | 
    750:
    LFLQCELTLC | TKMEKHPQKL | PKCVPPDEAC | TSLDASIIWA | MMQNKKTFTK | 
    800:
    PLAVIHHEAE | SKEKGPSMKE | PNPISPPIFH | GLDTLTVMGI | AFAAFVIGAL | 
    850:
    LTGALWYIYS | HTGETAGRQQ | VPTSPPASEN | SSAAHSIGST | QSTPCSSSST | 
    851:
    A
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    MIM:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human TGF-beta receptor type 3
    Cat.:
    E1949m
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    96T
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    ELISA Kit for Human TGF-beta receptor type 3
    Cat.:
    E1949h
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    96T
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    ELISA Kit for Human TGF-beta receptor type 3
    Cat.:
    E1949p
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    96T
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    ELISA Kit for Human TGF-beta receptor type 3
    Cat.:
    E1949r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TGF-beta receptor type 3
    Cat.:
    U1949h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TGF-beta receptor type 3
    Cat.:
    U1949p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human TGF-beta receptor type 3
    Cat.:
    U1949m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TGF-beta receptor type 3
    Cat.:
    U1949r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human TGF-beta receptor type 3
    Cat.:
    P1949Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TGF-beta receptor type 3
    Cat.:
    P1949Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TGF-beta receptor type 3
    Polyclonal Antibody for Human TGF-beta receptor type 3
    Cat.:
    P1949Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human TGF-beta receptor type 3
    Monoclonal Antibody for Human TGF-beta receptor type 3
    Monoclonal Antibody for Human TGF-beta receptor type 3
    Monoclonal Antibody for Human TGF-beta receptor type 3
    Protein for Human TGF-beta receptor type 3
    Protein for Human TGF-beta receptor type 3
    Protein for Human TGF-beta receptor type 3
    Protein for Human TGF-beta receptor type 3

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    Linearity
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    References
    1. 1.
      "Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors."
      Moren A. , Ichijo H. , Miyazono K.
      Biochem. Biophys. Res. Commun.189:356-362(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);VARIANT PHE-15
      tissue: Placenta.
    2. 2.
      "Eleven single nucleotide polymorphisms and one triple nucleotide insertion of the human TGF-beta III receptor gene."
      Zippert R. , Baessler A. , Holmer S.R. , Hengstenberg C. , Schunkert H.
      J. Hum. Genet.45:250-253(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT PHE-15
      tissue: Blood.
    3. 3.
      NIEHS SNPs program
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ASN-14; PHE-15; LEU-163; THR-635 AND ARG-765
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Tongue.
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    7. 7.
      "Identification of Tctex2beta, a novel dynein light chain family member that interacts with different transforming growth factor-beta receptors."
      Meng Q.-J. , Lux A. , Holloschi A. , Li J. , Hughes J.M.X. , Foerg T. , McCarthy J.E.G. , Heagerty A.M. , Kioschis P. , Hafner M. , Garland J.M.
      J. Biol. Chem.281:37069-37080(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TCTEX1D4
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